When hydrocodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

With the HYDROCODONE Discount Card, all patients are eligible to:

  • Save up to 85% off out-of-pocket costs*
  • Pay as little as $26 each month for your 120-ct prescription**
  • Reuse this coupon card – it never expires
Print Your Pre-activated Discount Card Today!
Show the pharmacist this card from your phone or tablet.
HYDROCODONE Prescription Discount Card

*Offer Details:

  • This Discount Card is not health insurance and cannot be used to lower your co-pay. The discount card price may be lower than your health insurance co-pay. Ask your pharmacist to help you find the best possible price.
  • This coupon card cannot be used in conjunction with any federal or state funded program, such as medicare or medicaid.
  • Card is accepted at over 68,000 participating pharmacies, may be used an unlimited number of times, and provides discounts on most medication.

To the Patient:

  • Simply print your HYDROCODONE Discount Card, it works like a coupon.
  • Present your HYDROCODONE Discount Card with your prescription to your pharmacy and you may pay less on your prescriptions.
  • On each 120-ct supply, your Discount Card may deduct from your out-of-pocket costs up to $139.**
  • Make sure to keep this Discount Card—do not leave it with the pharmacy. You will need to show your Discount Card for every prescription refill to get the savings.

To the Pharmacist:

Please use the card's BIN, PCN and Group number to adjudicate. For questions, please call 1-800-223-2146.

**Example savings are based on discounts from a prescription of HYDROCODONE/ACETAMINOPHEN 10mg/325mg Tablet. Prices vary by pharmacy and prescription and are subject to change over time. Ask your pharmacist for the actual discounted price.

Save on your HYDROCODONE Prescription Costs

The HYDROCODONE Discount Card was designed to help make HYDROCODONE prescriptions more affordable for patients. Below are some examples of actual savings. Ask your pharmacist for your discount price.

Prescription Quantity Retail Price Discounted Price Savings
HYDROCODONE/ACETAMINOPHEN 5mg/325mg Tablet20$28.99$10.6363.33%
HYDROCODONE/ACETAMINOPHEN 7.5mg/325mg Tablet90$95.99$30.2768.47%
HYDROCODONE/ACETAMINOPHEN 10mg/325mg Tablet120$164.69$26.1584.12%
HYDROCODONE/ACETAMINOPHEN 5mg/300mg Tablet20$52.99$38.3127.70%
HYDROCODONE/ACETAMINOPHEN 7.5mg/300mg Tablet20$45.39$26.9040.74%
HYDROCODONE/ACETAMINOPHEN 10mg/300mg Tablet30$80.59$55.0331.72%
HYDROCODONE/ACETAMINOPHEN 7.5mg/500mg Tablet60$92.59$22.6075.59%
  • Retail Price for 120 Tablets: $164.69
  • With Discount Card: $26.15
  • Save 84.12%
  • Retail Price for 60 Tablets: $92.59
  • With Discount Card: $22.60
  • Save 75.59%
  • Retail Price for 90 Tablets: $95.99
  • With Discount Card: $30.27
  • Save 68.47%
  • Retail Price for 20 Tablets: $28.99
  • With Discount Card: $10.63
  • Save 63.33%



    HYDROCODONE is a semi-synthetic opioid synthesized from codeine, one of the opioid alkaloids found in the opium poppy. It is a narcotic analgesic used orally as an antitussive/cough suppressant, but also commonly taken orally for relief of moderate to severe pain.

    HYDROCODONE bitartrate and acetaminophen tablets are indicated for the relief of moderate to moderately severe pain.

    HYDROCODONE bitartrate and acetaminophen is supplied in tablet form for oral administration.


    This product should not be administered to patients who have previously exhibited hypersensitivity to HYDROCODONE or acetaminophen.

    Patients known to be hypersensitive to other opioids may exhibit cross-sensitivity to HYDROCODONE.


    Dosage should be adjusted according to the severity of the pain and the response of the patient. However, it should be kept in mind that tolerance to HYDROCODONE can develop with continued use and that the incidence of untoward effects is dose related.

    The usual adult dosage is one or two tablets every four to six hours as needed for pain. The total daily dosage should not exceed 8 tablets.


    HYDROCODONE bitartrate and acetaminophen tablets, USP are available in the following strengths:

    • 2.5 mg/500 mg
    • 5 mg/500 mg
    • 7.5 mg/325 mg
    • 7.5 mg/500 mg
    • 7.5 mg/650 mg
    • 7.5 mg/750 mg
    • 10 mg/325 mg
    • 10 mg/500 mg
    • 10 mg/650 mg
    • 10 mg/660 mg
    • 10 mg/750 mg


    Store at controlled room temperature 15°-30°C (59°-86°F).

    Dispense in a tight, light-resistant container with a child-resistant closure.


Frequently Asked Questions

  • How does the HYDROCODONE Prescription Discount Card work? is partnered with companies that negotiate discounts directly with the pharmacies. These discounts are then passed directly on to cardholders.

  • Who is eligible for the HYDROCODONE Prescription Discount Card?

    The HYDROCODONE Prescription Discount Card has no requirements. Unlike insurance programs, there is no income, age, pre-existing condition, deductible, or waiting period restrictions. The free discount card is designed to help patients nationwide who do not have prescription drug coverage or who have coverage but are subject to large deductibles, large co-pays, formulary limitations, dosing limitations, gaps, and/or any cash out-of-pocket expenses.

  • How much does the HYDROCODONE Prescription Discount Card/Coupon cost?

    The HYDROCODONE Prescription Discount Card is absolutely FREE. We provide this service to every American that wishes to save on their HYDROCODONE prescription cost. There are no premiums or deductibles associated with this program whatsoever. The printable card/coupon is available free of charge from our website.

  • How do I use the HYDROCODONE Prescription Discount Card?
    1. Select a pharmacy: the HYDROCODONE Prescription Discount Card is valid at over 68,000 network pharmacy locations nationwide. In most cases, your current pharmacy will be part of our network.
    2. Submit your prescription: Present your HYDROCODONE prescription to the pharmacist. If you need to transfer a prescription, bring your empty prescription bottle or label with you to the pharmacy.
    3. Present your HYDROCODONE Prescription Discount Card: Your card's unique code provides the pharmacist with the appropriately discounted prescription price. The price on the prescription is based on the pharmacy's contracted agreement with and our partners.
    4. You Save: Your savings will be clear once the pharmacist enters your filled prescription into the register. Whether the lowest discount price is the HYDROCODONE Prescription Discount Card price, your present insurance program's price, or the pharmacy's already discounted price, you are GUARANTEED to receive the LOWEST price available!
  • Which pharmacies can I go to?

    We have a constantly expanding list of over 68,000 participating major chain pharmacies and local pharmacies nationwide including CVS/Pharmacy, Walgreens, Target Pharmacy, Walmart Pharmacy, Safeway, Rite Aid, and more!

  • How can I be assured I am getting the lowest price?

    The discounted price may vary by as much as 75% depending on the pharmacy discount rate contracted with While pharmacy prices may vary from week-to-week and by the geographic location, the patient is guaranteed the lowest price available regardless of whether it is the price, your present insurance program's price, or the pharmacy's already discounted price.

HYDROCODONE Safety Information


    Hepatotoxicity: Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products.

    The risk of acute liver failure is higher in individuals with underlying liver disease and in individuals who ingest alcohol while taking acetaminophen.

    Instruct patients to look for acetaminophen or APAP on package labels and not to use more than one product that contains acetaminophen. Instruct patients to seek medical attention immediately upon ingestion of more than 4000 milligrams of acetaminophen per day, even if they feel well.

    Serious skin reactions: Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. Patients should be informed about the signs of serious skin reactions, and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity.

    Hypersensitivity/anaphylaxis: There have been post-marketing reports of hypersensitivity and anaphylaxis associated with use of acetaminophen. Clinical signs included swelling of the face, mouth, and throat, respiratory distress, urticaria, rash, pruritus, and vomiting. There were infrequent reports of life-threatening anaphylaxis requiring emergency medical attention. Instruct patients to discontinue Hydrocodone Bitartrate and Acetaminophen Tablets, USP immediately and seek medical care if they experience these symptoms. Do not prescribe Hydrocodone Bitartrate and Acetaminophen Tablets, USP for patients with acetaminophen allergy.

    Respiratory Depression: At high doses or in sensitive patients, hydrocodone may produce dose-related respiratory depression by acting directly on the brain stem respiratory center. Hydrocodone also affects the center that controls respiratory rhythm, and may produce irregular and periodic breathing.

    Head Injury and Increased Intracranial Pressure: The respiratory depressant effects of narcotics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, other intracranial lesions or a pre-existing increase in intracranial pressure. Furthermore, narcotics produce adverse reactions which may obscure the clinical course of patients with head injuries.

    Acute Abdominal Conditions: The administration of narcotics may obscure the diagnosis or clinical course of patients with acute abdominal conditions.


    Special Risk Patients: As with any narcotic analgesic agent, hydrocodone bitartrate and acetaminophen tablets should be used with caution in elderly or debilitated patients and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy or urethral stricture. The usual precautions should be observed and the possibility of respiratory depression should be kept in mind.

    Cough Reflex: Hydrocodone suppresses the cough reflex; as with all narcotics, caution should be exercised when hydrocodone bitartrate and acetaminophen tablets are used postoperatively and in patients with pulmonary disease.


    The most frequently reported adverse reactions are lightheadedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in nonambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.

    Other adverse reactions include:

    Central Nervous System: Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, mood changes.

    Gastrointestinal System: Prolonged administration of hydrocodone bitartrate and acetaminophen tablets may produce constipation.

    Genitourinary System: Ureteral spasm, spasm of vesical sphincters and urinary retention have been reported with opiates.

    Respiratory Depression: Hydrocodone bitartrate may produce dose-related respiratory depression by acting directly on the brain stem respiratory center (see OVERDOSAGE).

    Special Senses: Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.

    Dermatological: Skin rash, pruritus.

    The following adverse drug events may be borne in mind as potential effects of acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis.


    Controlled Substance:

    Hydrocodone Bitartrate and Acetaminophen Tablets are classified as a Schedule II controlled substance.

    Abuse and Dependence:

    Psychic dependence, physical dependence, and tolerance may develop upon repeated administration of narcotics; therefore, this product should be prescribed and administered with caution. However, psychic dependence is unlikely to develop when hydrocodone bitartrate and acetaminophen tablets are used for a short time for the treatment of pain.

    Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only after several weeks of continued narcotic use, although some mild degree of physical dependence may develop after a few days of narcotic therapy. Tolerance, in which increasingly large doses are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of analgesic effect, and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients.


    Following an acute overdosage, toxicity may result from hydrocodone or acetaminophen.

    Signs and Symptoms:

    Hydrocodone: Serious overdose with hydrocodone is characterized by respiratory depression (a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.

    Acetaminophen: In acetaminophen overdosage: dose-dependent, potentially fatal hepatic necrosis is the most serious adverse effect. Renal tubular necrosis, hypoglycemic coma, and coagulation defects may also occur. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis and general malaise. Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion.


    A single or multiple drug overdose with hydrocodone and acetaminophen is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended. Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption. Oxygen, intravenous fluids, vasopressors, and other supportive measures should be employed as indicated. Assisted or controlled ventilation should also be considered.

    For hydrocodone overdose, primary attention should be given to the reestablishment of adequate respiratory exchange through provision of a patent airway and the institution of assisted or controlled ventilation. The narcotic antagonist naloxone hydrochloride is a specific antidote against respiratory depression which may result from overdosage or unusual sensitivity to narcotics, including hydrocodone. Since the duration of action of hydrocodone may exceed that of the antagonist, the patient should be kept under continued surveillance, and repeated doses of the antagonist should be administered as needed to maintain adequate respiration. A narcotic antagonist should not be administered in the absence of clinically significant respiratory or cardiovascular depression.

    Gastric decontamination with activated charcoal should be administered just prior to N-acetylcysteine (NAC) to decrease systemic absorption if acetaminophen ingestion is known or suspected to have occurred within a few hours of presentation. Serum acetaminophen levels should be obtained immediately if the patient presents 4 hours or more after ingestion to assess potential risk of hepatotoxicity; acetaminophen levels drawn less than 4 hours post-ingestion may be misleading. To obtain the best possible outcome, NAC should be administered as soon as possible where impending or evolving liver injury is suspected. Intravenous NAC may be administered when circumstances preclude oral administration.

    Vigorous supportive therapy is required in severe intoxication. Procedures to limit the continuing absorption of the drug must be readily performed since the hepatic injury is dose dependent and occurs early in the course of intoxication.